This'll probably be short, because I don't know how long a window I'll have to post it before the site goes wonky again. Besides, it's awkward, because it's the first story (I think) of a larger arc, or at least the setup for something later on, and so it's kinda weird to cover.
The thing that bothers me the most about Elaine, I think, is that she has just such a melange of psychic powers. She's telepathic, and empathic, and she can call/see spirits, and she can "read" the past, and she can sense cancer too? It's just... gah. She's like a whole little ball of Generic Supernatural Powers.
Also, the story itself just feels a bit rushed and condensed, because it's all taking place in one issue. The investigation is pretty much laughable, the climax is decent but still fairly brief... it works alright as a setup for future, interesting stuff, but if it were a story in its own right it wouldn't stand on its own as well.
A few other bits: I really liked the Grandmas, and wonder how she got introduced to them in the first place. (I mean, only two of them could be her own actual grandmothers, maybe two are, and one was a great-grandma or something? But if not, where'd they come from?) I also liked the quick reference to Death, ie: the girl that was following Mona around.
What I didn't like so much was the art. Man, for such generally good writing, it's paired with some questionable artists! *sigh*